02 Apr
Senior Scientist, BMD Biotherapeutic Production

Vacancy expired!


Pfizer's BioMedicine Design Biotherapeutic Expression and Purification group (BEP) is seeking a protein biochemist. Qualified candidate will play an essential role in a high-energy protein purification research laboratory. The purification group is responsible for non-GMP protein drug lead generation, supporting the various Pfizer research units and their pre-clinical therapeutic in-vitro and in-vivo needs. The candidate will be responsible for processing of mammalian- expressed recombinant protein modalities including, but not limited to, monoclonal antibodies using state-of-the-art technologies and equipment. The candidate will contribute to the group wide deliverables and be required to work on several projects simultaneously presenting results and updates at group meetings.


  • Provide scientific guidance for the protein biochemistry group supporting early discovery

  • Develop efficient and scalable purification processes for novel biotherapeutic candidates

  • Provide highly-purified biotherapeutic candidates to discovery project teams

  • Drive technology innovation; design and implement automation strategies for high-throughput protein purification and analysis

  • Work closely with multidisciplinary teams including therapeutic discovery teams, BEP Transient production group, research units, and BTxPS

  • Occasional travel to Cambridge, MA


  • A PhD with 0-3 years of relevant experience or MS with 7+ years of relevant experience in Biochemistry, Biology, Biomedical Sciences or a related discipline along with a solid understanding of biotherapeutic production

  • Demonstrated technical expertise in protein purification

  • Strong understanding of analytical biochemistry and experience in protein characterization techniques

  • Experience and knowledge in the operation of AKTA and Agilent chromatography systems

  • Strong communication skills, written and oral

  • Strong organizational skills

  • People Mentorship experience

  • Prior experience in therapeutic protein discover and biochemistry research


  • Pharmaceutical industry experience highly preferred

  • Experience operating Unicorn, Empower, and ChemStation

  • Python and/or VB experience

  • Experience in purification process development and process automation

  • Proven track record in project delivery


  • Eligible for Employee Referral Bonus: Yes

  • Last Date to Apply: April 15, 2020

  • LI-PFE

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Research and Development

Vacancy expired!